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Livestock Laboratories & Biosciences Inc.

Livestock Labs creates and supplies genetically engineered cell lines designed to grow predictably, stably, and economically.

San Francisco, CA, USA

One Liner

One Liner
Livestock Labs creates and supplies genetically engineered cell lines designed to grow predictably, stably, and economically.

What Problem We are Solving

Problem
Cultivated meat and other biotech companies want their cells to have specific characteristics. Unfortunately, nearly all cell lines on the market only offer one or two desired traits and often come with unwanted side effects.

Livestock Labs has developed a patentable genetic engineering process that enables us to deliver dozens of characteristics with precision, all in a regulatory-compliant manner.

 

About Us

About Us
Founded by industry veterans (Mission Barns & New Age Eats), Livestock Labs aims to expedite the growth of the cultivated meat industry by providing access to off-the-shelf capable cell lines. 

Company: 
Livestock Labs uses advanced genetic engineering, data analytics, and machine learning technology to create patently superior cell lines from different livestock species designed to grow predictably, stably, and economically, specifically for the cultivated meat industry. 

For companies working on cultivated meat: 
Beyond offering superior cell lines, we can reduce cell line development costs by up to 95% and save them between 16 and 24 months of R&D. 

For investors: 
Livestock Labs is capital-efficient because our sole focus is on creating and licensing cell lines. We only need a small lab, a handful of employees, and a relatively small financial investment before generating significant revenues. Livestock Labs' gross margins rival those of software companies. 

Venture Highlights

Highlights
 

Recent Traction: Between founding and now:

  • Completed pre-seed funding ($400k) (willing to oversubscribe)
  • Multiple LOIs and NDAs: Merck, Wacker, Vow, Multus Bio, Hill’s Pet Nutrition, and more
  • Secured top-tier patent attorney Chris Holly from Cooley LLP.
  • As of October 2023, Livestock Labs is operating out of Cell Valley Labs, Berkeley, USA, a co-working lab space where experimental work is underway to build our MVP.
  • Completed three incubators/accelerators: ProVeg Incubator (2023), Batchery (2023), and Plug and Play (2024)
  • Tech Updates
    • Generated and sequence-verified four genetic constructs, including the two targeting constructs required to generate our porcine-based mvp.
    • Began sourcing fibroblasts, myoblasts/satellite cells, and adipose-derived mesenchymal stem cell cells from Bos taurus (cow), Sus scrofa (pig), and Ovis aries (sheep).
    • Initiated computational analyses to identify additional novel genetic switches for use in inducible gene regulation using FDA-approved food-appropriate compounds (FACs).
    • Completed construction and validated functionality of gene-targeting constructs for pig cells.
    • Received and banked fibroblasts, adipose-derived stem cells (ADSCs), and myoblasts/satellite cells (SCs) derived from pig and sheep.
    • Received and banked fibroblasts and adipose-derived stem cells (ADSCs) derived from cow.
    • Determined population doubling time (PDT) of several fibroblast lines, including those derived from pig.
    • Confirmed correct karyotype (38, XY) of two pig fibroblast lines used for gene targeting.
    • Performed first gene targeting experiments on pig fibroblast lines: there are currently 20 lines of interest. These are being expanded, banked, and undergoing further genetic characterization to ensure they have been correctly targeted.
    • Using machine learning and data analytics, we have identified at least 21 novel transcription factor - FDA-approved compound pairs that could be incorporated as inducible switches in future engineered cell lines.
 

Business Model

Business Model
● Develop superior cell lines, starting with the major livestock species.
● Patent those cell lines and the technology used to develop them.
● License those cells to all companies that can benefit from them.
● Collect royalties from those who sell a final product that includes Livestock Labs cells.

Competitive Advantage

Quote
Team:
LL was founded by industry veterans (Mission Barns & New Age Eats)
with the skill sets to take LL from zero to unicorn status.

Steen Ooi, PH.D. CEO & CSO (Full Time)
The founder, CEO, and CSO, Dr. Steen Ooi (SO), is a senior scientist with over twenty-three years of research experience employing transgenic technologies to create genetically engineered cell lines and animals, tissue culture, organoids, and bioinformatics. These have been applied to various research fields, including immunology, signal transduction, gene regulation, DNA methylation, epigenetics, stem and germ-cell developmental biology, and reproductive toxicology. As principal investigator (PI) of the Laboratory of Epigenetic Signaling at University College London Cancer Institute (UCL-CI), his laboratory investigated fundamental mechanisms regulating epigenetic information, which controls how genes are correctly regulated and are perturbed in various diseases such as cancer. During this time, as well as contributing to both undergraduate and graduate-taught courses, SO directed a team of five postdoctoral researchers and five research associates and mentored twelve graduate and undergraduate students. In his role as Lead Scientist in the Division of Porcine Cell Engineering at New Age Eats, he led a team of five researchers in creating and characterizing the company’s porcine cell lines, which were screened for sensory qualities, suspension growth and incorporated with plant-based formulations into hybrid food products.

Andrew Sayles COO (Full Time)
Co-founder and COO Andrew Sayles has a strong business development and operations background. At England Logistics, he excelled in sales and operations, steering a satellite office and leading a robust team to achieve record profits, adeptly handling P&L statements, budgets, and forecasts. At Mission Barns, a cultivated fat company, he was involved in several senior, non-technical roles, helping the company transition from its bench- to pilot-scale facility and liaising with government agencies, NGOs, investors, and corporations worldwide to champion the advancement of cultivated meat.


Timing:
Currently, zero companies provide access to off-the-shelf capable cell
lines designed for the unique requirements of CM. The CM industry has reached
the age of specialization, and by being the first to fully embrace the best
technology available (genetic engineering, machine learning, and data analytics)
with the intent of supplying the industry, we can create a monopoly on cell lines
and be the sole supplier for companies working on CM tech for years/decades to
come: all of this will be protected by an ever-widening IP moat.

Capital Efficient:
As a B2B cell line developer and supplier, LL doesn’t have to spend
money on obtaining regulatory approval, consumer marketing, or large,
capital-intensive facilities. We can solely focus on creating what every company
working on cultivated meat tech requires: predictable, economical, stable,
nutritious, and flavorful cell lines.

Revenue

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Burn Rate
$5K

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Customer Costs

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Margins
97%

Go-To Market Strategy

Business Strategy
 Strategy Overview

Product Development Timeline:


  • MVP Launch: Scheduled for Q4 2024, focusing on piloting minimally characterized cell lines that demonstrate Livestock Labs' (LL) promising technology. 
  • Continuous Improvement: Between Q4 2024 and Q4 2025, LL will collaborate closely with select partners to refine and fully characterize the cell lines based on real-world feedback and requirements. 

Strategic Partnerships:

  • LOI Collection: Starting Q2 2024, LL will begin collecting Letters of Intent (LOIs) from potential strategic partners.
  • Selection and Collaboration: Out of the received LOIs, LL will select five to ten partners for initial collaborations, offering them access to our cell lines at no cost in exchange for detailed feedback and collaboration on product refinement.

Value Proposition for Selected Collaborators:

  • Cost-Efficiency: Initial cell lines will be offered at no charge to selected partners, mitigating their R&D risks and costs. 
    • It would be unwise to sell a cell line that has yet to be fully characterized, as it could potentially harm LL's reputation. In 2025, the goal is to build excitement and anticipation for our cell lines, so
      when LL launches its fully characterized cell lines publicly, it can dominate the market by winning over 90-95% of it, not just 10-20%. 
  • Influence on Product Development: Partners who join us early on will have the exclusive opportunity to influence the development of our cell lines, which can be highly beneficial to their company. By working with us to develop cell lines tailored to their particular needs, whether for a specific species or tissue type, bioreactor or scaffold design, or media formulation, they can better leverage our technology to their advantage. The earlier a partner starts working with LL, the more effectively they can utilize our cell lines to enhance their own technology. 
  • Preferential Pricing and Access: Early collaborators will receive preferential terms and early access to our fully characterized cell lines once launched, giving them a competitive advantage. 
    • By collaborating early, they will help us identify and fix any issues that may arise from launching a new product. This will be crucial to achieving a market share of over 90% upon our public launch, which must be near flawless.

Market Launch and Public Introduction:

  • Full Product Launch: Scheduled for 2026, following a year of extensive characterization, patenting, and regulatory certifications (generally recognized as safe (GRAS)). 
  • Building Hype: Throughout 2025, LL will engage in targeted marketing and promotional activities, including trade shows and strategic publications, to build anticipation and demand for our cell lines.

Sales and Outreach Strategy:

  • Direct Outreach: Utilizing the founders’ extensive network, LL will engage directly with C-level executives and decision-makers within the CM industry. 
  • Strategic Visibility: Participation in key industry events and presence in relevant publications will be used to showcase LL’s advancements and attract additional partners and customers.

 


 

Competitive Analysis

Competitive Analysys
We have yet to identify a competitor that specifically seeks to offer genetically engineered, fully characterized, and FDA-appropriate cell lines to the cultivated meat industry. Although cell lines can be purchased from multiple commercial vendors (e.g., ATCC, ThermoFisher, Sigma), these are unsuitable for cultivated meat. For example, whilst ATCC offers cell lines from different animals, including livestock species, these were created for biomedical and pharmacological R&D, not food production, as reflected in their creation strategies. Additionally, there are currently no commercially available cell lines of livestock origin designed and tested for the large-scale production of biomass. Finally, the fact that most commercially available cell lines were not originally designed for human consumption means: 1) sensory qualities are unaccounted for, ignoring consumer experience; and 2) there is a paucity of key information in provenance-related records: this renders them unsatisfactory from a regulatory perspective.
Competitor Website
Creative Bioarray www.creative-bioarray.com
AcceGen Biotechnology www.accegen.com
Extracellular www.extracellular.com

Networking

Networking
We are open to meeting up to grab a coffee, or just to chat. We would really enjoy your feedback and insight into our venture and would be happy to discuss anything that you are currently working on to see if we can be of service!

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Capital

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Name Amount
Amount Left $100,000.00
Amount Raised (This Round) $400,000.00
Amount Raise To Date $400K
Investment Type N/A
Type of Raise SAFE

Valuation
$5M
Preseed
$400K

TAM SAM SOM

TAM
$542B
SAM
$582M
SOM
$90M

Business Stage

Business Stage
Business Plan Mapped Out

Business Type

Business Types
Venture Capital Backed

Categories

Sustainability
Future Tech
CleanTech
B2B
Food
Technology
Environment
Engineering
Biotechnology
Agriculture

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Last Updated: 08/23/24