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SOSV

Deep Tech for Human and Planetary Health

Princeton, NJ, USA

Description

SOSV is a global, multi-stage venture capital firm and accelerator platform focused on deep technology startup investing — especially around human and planetary health, climate tech, life sciences, hardware, and hard tech innovations. Founded in 1995 by Sean O’Sullivan, SOSV combines deeply resourced development programs with long-term venture capital support that begins at pre-seed and extends into later rounds. 

Specific Funding Stage
Pre-Seed / Seed (Core Focus)

  • SOSV typically makes its initial investment at pre-seed / early seed for startups that join its flagship development programs (e.g., HAX, IndieBio, Orbit). 

  • These programs are designed to accelerate technology, product, and team development before external fundraising. 

Series Seed / Series A / Later Follow-On

  • SOSV continues to invest follow-on capital into portfolio companies as they progress through Series Seed, Series A, and later rounds — but usually only if SOSV invested at pre-seed. 

Investment Amount and Percentage Equity (Company-Level)
Check Sizes / Typical Funding

  • SOSV’s pre-seed checks typically fall in the ~$250,000 to $550,000 range, depending on the program and startup needs. 

  • Some founder reports cite ~$250,000 as SOSV’s standard early ticket in accelerator programs that also help with fundraising momentum. 

Equity Taken

  • SOSV does not publicly disclose a uniform equity percentage across all investments (equity terms are negotiated deal by deal).

  • As an active investor through pre-seed to Series, SOSV usually holds minority, non-controlling positions appropriate for early-stage venture capital.

Contextual Approach

  • SOSV’s investments are tied to startup development programs where capital is paired with deep technical resources, facilities, and mentorship — effectively blending program support + capital at early stages. 

Equity Structure
  • Early investments are typically made via standard venture instruments appropriate for early stage (e.g., SAFEs/notes converting to equity upon priced rounds).

  • SOSV deploys capital through program entry and subsequent rounds, often participating alongside co-investors in seed and later financing. 

  • There are no universal public terms on equity percentages comparable to fixed accelerator models — terms vary by company, program, and stage.

Application / Submission Method
Submission Channels

  • Founders typically apply to SOSV’s startup development programs (e.g., HAX for hard/deep tech, IndieBio for life sciences, and others like Orbit). 

  • Applications run through SOSV’s websites for each program; they operate in regions such as New York City, San Francisco, and Newark (U.S.), among others. 

Interaction

  • Accepted companies work closely with SOSV partners, mentors, and technical teams during the program and beyond. Decisions to invest follow this intensive engagement.

Eligibility

Program Application: Founders apply to a specific SOSV development program (e.g., HAX, IndieBio).

Selection & Screening: SOSV evaluates fit based on technology depth and potential impact.

Program Engagement: Accepted teams enter the development program with structured support.

Pre-Seed Investment: SOSV typically makes an initial investment concurrent with or shortly after program entry.

Follow-On Evaluation: SOSV assesses product progress and market traction for potential additional funding in seed and later rounds.

Process

Sector Focus

  • Deep Tech: Hard tech, robotics, advanced manufacturing, and hardware systems. 

  • Life Sciences & Health: Biotech, diagnostics, therapeutic platforms, and related areas (via IndieBio). 

  • Climate & Planetary Health: Decarbonization, sustainable food systems, materials, energy, and other climate innovations. 

Geography

  • Global — SOSV has backed founders from dozens of countries and maintains development programs in the U.S., Asia, and Europe

Stage

  • Early sampling through pre-seed and seed via program entry; follow-on participation into Series A and later rounds

Team Profile

  • Founders aiming to solve complex scientific, engineering, or planetary challenges with technologies requiring deep R&D and capital.

What an Applicant can Obtain

Pre-Seed Capital: Early funding (~$250K–$550K) tied to accelerator participation. 

Technical & Lab Resources: Access to advanced facilities (e.g., fabrication shops, labs). 

Deep Mentorship: Support from SOSV engineers, scientists, design experts, and partners. 

Ecosystem Access: Introductions to co-investors and corporate partners, plus SOSV’s VC-Founder Matchups and global network. 

Follow-On Support: Continued investment into seed, Series A, and beyond for participating portfolio companies.