Description

• Target Stages: Primarily focuses on Pre-Seed, Seed, and Series A funding.
• Gap Bridge: It is designed to bridge the funding "chasm" between pre-seed stages and Series B rounds.
• Series B and Beyond: While focused on early stages, the fund has participated in Series B rounds (e.g., Indigo Biosciences) and seen portfolio companies progress to Series D. 
• Method: Founders can engage through the LSG Investments "Get Funded" portal.
• Initial Inquiry: Applicants typically start with a screening process where their business plan, milestones, and technology are reviewed.
• Special Grants: Early-stage founders still in the "germination stage" can be invited to apply for Business Opportunity Grants, which fund market studies and technical/legal consulting. 
• Rolling Intake: LSGPA reviews applications and invests on an ongoing basis throughout 2026.
• Ecosystem Events: Related opportunities often occur during the Life Sciences Future meeting, which is scheduled for September 30 – October 1, 2026, in King of Prussia, PA. 

Eligibility

• Geography: Strictly limited to companies based in or significantly impacting Pennsylvania, with a core focus on Central Pennsylvania.
• Sectors: Core activity is in Drug Discovery, Diagnostics, Medical Devices, and Health IT.
• Business Profile: Targets "young" companies tackling large-scale healthcare challenges or product-commercialization constraints.

Process

1. Intake & Screening: Initial review of technical and commercial viability.
2. Due Diligence: A venture-level, intensive deep-dive into the business plan and technology. LSGPA typically incurs these costs prior to making a formal investment.
3. Active Partnership: Once funded, LSGPA provides ongoing support by serving as a director or board observer and offering management advice.
4. Evergreen Reinvestment: As an evergreen fund, returns from successful exits are reinvested into the next generation of startups. 

What an Applicant can Obtain

• Direct Capital: Funding to help bring life-changing technologies to market.
• Operational Expertise: Access to a curated network for scientific advice and business development.
• Market Signal: Because of their rigorous due diligence, funding from LSGPA often serves as a signal of investability to other venture capitalists.